BDBM10972 (3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-heptylcarbamate::CHEMBL433041::Eptastigmine::Heptylphysostigmine
SMILES [H][C@]12N(C)CC[C@@]1(C)c1cc(OC(=O)NCCCCCCC)ccc1N2C
InChI Key InChIKey=RRGMXBQMCUKRLH-CTNGQTDRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 10972
Affinity DataKi: 100nMAssay Description:Binding affinity to AChE (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibitory activity against acetylcholinesterase in mice at the dose of 4.8 mg/kg via intraperitoneal administrationMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of Acetylcholinesterase(AChE) from human RBCMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Compound was evaluated in vitro in rats for the inhibition of brain (striatal) acetylcholinesterase (AChEI) using acetylthiocholine as substrate; 0.0...More data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:Compound was evaluated in vitro for the inhibition of human serum Butyrylcholinesterase using butyrylthiocholine as substrate; 0.00029-0.001More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human erythrocytes AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human plasma AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against acetylcholinesterase in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Inhibitory activity against acetylcholinesterase in human RBCMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against human AchE (Acetylcholinesterase)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair