BDBM112408 US8623889, 407

SMILES Cc1c(Cl)c(ncc1-c1ccc2cc(NC(=O)C3C[C@@H]3F)ncc2c1)[C@@H](O)C(F)(F)F

InChI Key InChIKey=IWQCEBSBUKDCDT-GSTZGWFYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 112408   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112408(US8623889, 407)
Affinity DataKi:  0.0841nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112408(US8623889, 407)
Affinity DataKi:  2.02nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent