BDBM11242 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide::med.21724, Compound 76::niclosamide
SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(cc1Cl)[N+]([O-])=O
InChI Key InChIKey=RJMUSRYZPJIFPJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 29 hits for monomerid = 11242
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University
National Taiwan University
Affinity DataIC50: >5.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of YFP tagged ANO1 (unknown origin) expressed in FRT cells incubated for 24 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Src kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Flt3 after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of JAK2 after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of JNK1 after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PDGFR-beta after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of STAT3 in human HeLa cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of EGFR after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of Src kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of FGFR-1 after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of VEGFR2 after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of LYN after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of KIT after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.41E+4nMAssay Description:Inhibition of Aurora-A after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.94E+4nMAssay Description:Inhibition of Akt1 after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.78E+4nMAssay Description:Inhibition of TIE2 after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.75E+4nMAssay Description:Inhibition of GSK3-beta after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.39E+4nMAssay Description:Inhibition of PDK1 after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Abl1 after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of B-Raf after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Erk2 after 60 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Ten-point DRCs were generated for each drug. Vero cells were seeded at 1.2 × 104 cells per well in DMEM, supplemented with 2% FBS and 1× ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University
National Taiwan University
Affinity DataIC50: >5.00E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University
National Taiwan University
Affinity DataIC50: >5.00E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University
National Taiwan University
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of SARS Co-V 3CL proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of STAT3 phosphorylation in human MDA-MB-231 cells by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PKC-alpha after 60 mins by radiometric assayMore data for this Ligand-Target Pair