BDBM113301 US9695194, 17

SMILES COc1ccc(c(OC)c1)-c1nc2cc(OC)c(OC)cc2c(=O)o1

InChI Key InChIKey=JCFSQIOFMQLSPV-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 113301   

TargetCathepsin G(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113301(US9695194, 17)
Affinity DataKi:  100nM ΔG°:  -9.93kcal/molepH: 7.2 T: 2°CAssay Description:Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKallikrein-7(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113301(US9695194, 17)
Affinity DataKi:  175nM ΔG°:  -9.58kcal/molepH: 7.2 T: 2°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113301(US9695194, 17)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.51kcal/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKallikrein-14(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113301(US9695194, 17)
Affinity DataKi:  1.10E+3nM ΔG°:  -8.45kcal/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetChymotrypsin-C(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113301(US9695194, 17)
Affinity DataKi:  1.20E+3nM ΔG°:  -8.40kcal/molepH: 7.2 T: 2°CAssay Description:Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113301(US9695194, 17)
Affinity DataKi: >1.00E+4nM ΔG°: >-7.09kcal/molepH: 8.3 T: 2°CAssay Description:Materials: Thrombin (Chromogenics, cat. no. 820712), Substrate S-2288 (Chromogenics, cat. no. 82 08 52). Thrombin activity was determined at 37° ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113301(US9695194, 17)
Affinity DataKi: >1.00E+4nM ΔG°: >-7.09kcal/molepH: 7.2 T: 2°CAssay Description:Materials: Trypsin, 100 ug (Roche, sequence grade, Mw 23500), Substrate S-2288 (Chromogenics, cat. no. 820852). Trypsin activity was determined at 3...More data for this Ligand-Target Pair
In DepthDetails US Patent