BDBM11533 (1S,3S,5S)-2-[(2S)-2-amino-3,3-dimethylpentanoyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile; 2,2,2-trifluoroacetic acid::(S)-2-(1,1-Dimethylprop-1-yl)glycine-L-cis-4,5-methanoprolinenitrile TFA salt::BMS-477118::Saxagliptin Analogue 10a
SMILES CCC(C)(C)[C@H](N)C(=O)N1[C@H]2C[C@H]2C[C@H]1C#N
InChI Key InChIKey=APAZYVZBHAXPLE-VPOLOUISSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 11533
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Bristol-Myers Squibb Pharmaceutical Research Institute
Affinity DataKi: 7.10nM ΔG°: -11.0kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair