BDBM115424 US8637500, 293
SMILES CC(C)C(=O)N1CCC(CC1)c1cccnc1Oc1ccc(Nc2ccc(C)cn2)cc1
InChI Key InChIKey=QZBCULJJCAXKLK-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 115424
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Amgen
US Patent
Amgen
US Patent
Affinity DataIC50: 0.0980nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 μL of serial diluted PDE10A (BPS Bi...More data for this Ligand-Target Pair