BDBM11640 3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfamoylphenyl)thiourea::CHEMBL361827::Compound 9::fluorine-containing thiourea 9

SMILES NS(=O)(=O)c1ccc(NC(=S)NNc2c(F)c(F)c(F)c(F)c2F)cc1

InChI Key InChIKey=VPQCNGWOFGWYOE-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 11640   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11640(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Affinity DataKi:  15nM ΔG°:  -10.6kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11640(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Affinity DataKi:  15nMAssay Description:Inhibitory constant against human Carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universita Degli Studi

Curated by ChEMBL
LigandPNGBDBM11640(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against catalytic domain of human carbonic anhydrase XIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11640(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Affinity DataKi:  19nM ΔG°:  -10.4kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11640(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Affinity DataKi:  19nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11640(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Affinity DataKi:  25nMAssay Description:Inhibitory activity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Naples 'Federico Ii

Curated by ChEMBL
LigandPNGBDBM11640(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Affinity DataKi:  78nMAssay Description:Inhibitory constant against human Carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Naples 'Federico Ii

Curated by ChEMBL
LigandPNGBDBM11640(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Affinity DataKi:  84nMAssay Description:Inhibitory activity against human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed