BDBM11870 4-{[4-(4-Chlorophenoxy)phenyl]sulfonyl}-N-hydroxy tetrahydro-2H-pyran-4-carboxamide::4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxyoxane-4-carboxamide::alpha-sulfone 21
SMILES ONC(=O)C1(CCOCC1)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1
InChI Key InChIKey=HBYRXCFAHCMHAA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 11870
Affinity DataKi: <0.100nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 18.1nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
Affinity DataKi: 435nM ΔG°: -8.67kcal/molepH: 7.5 T: 2°CAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
Affinity DataKi: 590nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of MMP-7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human MMP9 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human MMP13 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP3 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human MMP8 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human MMP2 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human MMP14 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 435nMAssay Description:Inhibition of human MMP1 expressed in human HT-1080 cells assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluoromet...More data for this Ligand-Target Pair