BDBM119274 US8673906, 3.34::US9718800, 3.34

SMILES CC(Nc1cc(F)cc(c1)C#C)c1cc(cc2c1oc(cc2=O)N1CCOCC1)C(=O)N(C)C

InChI Key InChIKey=DEKGPMXJEWJVKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119274   

LigandPNGBDBM119274(US8673906, 3.34 | US9718800, 3.34)
Affinity DataIC50:  4nMT: 2°CAssay Description:Compounds in 100% DMSO were added to assay plates by acoustic dispensing. PI3Kβ was added in a Tris buffer (50 mM Tris pH7.4, 0.05% CHAPS, 2.1 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM119274(US8673906, 3.34 | US9718800, 3.34)
Affinity DataIC50:  4nMAssay Description:The inhibition of PI3Kβ, PI3Kα, PI3Kγ and PI3Kδ was evaluated in a Kinase Glo based enzyme activity assay using human recombinant...More data for this Ligand-Target Pair
In DepthDetails US Patent