BDBM1193 (2R,3S,4S,1 S,2 R)-4-[[(1,1-Dimethylethoxy0carbonyl]amino]-3-hydroxy-2-[(4-methoxybenzyl)amino]-5-phenylpentan(2 -hydroxy-1 indanyl)amide::2-Aminobenzyl-Substituted AHPPA deriv. 7::tert-butyl N-[(2S,3R,4R)-3-hydroxy-4-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}-4-{[(4-methoxyphenyl)methyl]amino}-1-phenylbutan-2-yl]carbamate

SMILES COc1ccc(CN[C@H]([C@H](O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)cc1

InChI Key InChIKey=VSKGJQQOHQMSIK-PGVCKJCBSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1193   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sandoz Research Institute

LigandPNGBDBM1193((2R,3S,4S,1 S,2 R)-4-[[(1,1-Dimethylethoxy0carbony...)
Affinity DataKi:  65nM ΔG°:  -10.2kcal/molepH: 6.25 T: 2°CAssay Description:Enzymatic activity was measured by following cleavage of the substrate H-Lys-Ala-Arg-Val-Leu-pNph-Glu-Ala-Nle-NH2. Products of the cleavage reaction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sandoz Forschungsinstitut Ges.M.B.H.

Curated by ChEMBL
LigandPNGBDBM1193((2R,3S,4S,1 S,2 R)-4-[[(1,1-Dimethylethoxy0carbony...)
Affinity DataKi:  147nMAssay Description:Inhibitory activity was determined against HIV type 1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed