BDBM119301 US8673906, 4.2::US9718800, 4.20

SMILES CC(Nc1cc(F)cc(F)c1)c1cc(cc2c1oc(cc2=O)N1CCOCC1)C(=O)N1CCC[C@@H]1CO

InChI Key InChIKey=NTCLMZDHZZNGLK-CAWMZFRYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119301   

LigandPNGBDBM119301(US8673906, 4.2 | US9718800, 4.20)
Affinity DataIC50:  5nMT: 2°CAssay Description:Compounds in 100% DMSO were added to assay plates by acoustic dispensing. PI3Kβ was added in a Tris buffer (50 mM Tris pH7.4, 0.05% CHAPS, 2.1 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM119301(US8673906, 4.2 | US9718800, 4.20)
Affinity DataIC50:  5nMAssay Description:The inhibition of PI3Kβ, PI3Kα, PI3Kγ and PI3Kδ was evaluated in a Kinase Glo based enzyme activity assay using human recombinant...More data for this Ligand-Target Pair
In DepthDetails US Patent