BDBM119321 US8673906, 9::US9718800, 9.0

SMILES CC(Nc1ccc(F)cc1)c1cc(cc2c1oc(cc2=O)N1CCO[C@H](C)C1)C(=O)N(C)C

InChI Key InChIKey=GMWIXYJWVBNHHV-AAFJCEBUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119321   

LigandPNGBDBM119321(US8673906, 9 | US9718800, 9.0)
Affinity DataIC50:  5nMT: 2°CAssay Description:Compounds in 100% DMSO were added to assay plates by acoustic dispensing. PI3Kβ was added in a Tris buffer (50 mM Tris pH7.4, 0.05% CHAPS, 2.1 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM119321(US8673906, 9 | US9718800, 9.0)
Affinity DataIC50:  5nMAssay Description:The inhibition of PI3Kβ, PI3Kα, PI3Kγ and PI3Kδ was evaluated in a Kinase Glo based enzyme activity assay using human recombinant...More data for this Ligand-Target Pair
In DepthDetails US Patent