BDBM119468 US8680120, 25-18

SMILES COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1cccc(F)c1


Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119468   

TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kissei Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM119468(US8680120, 25-18)
Show SMILES COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1cccc(F)c1
Show InChI InChI=1S/C23H18FNO3/c1-28-20-8-9-21-18(12-20)13-22(16-5-3-7-19(24)11-16)25(21)14-15-4-2-6-17(10-15)23(26)27/h2-13H,14H2,1H3,(H,26,27)
Affinity DataIC50: 17nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair