BDBM119472 US8680120, 25-28

SMILES COc1cc2cc(-c3ccccc3F)n(Cc3cccc(n3)C(O)=O)c2cc1F


Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119472   

TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kissei Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM119472(US8680120, 25-28)
Show SMILES COc1cc2cc(-c3ccccc3F)n(Cc3cccc(n3)C(O)=O)c2cc1F
Show InChI InChI=1S/C22H16F2N2O3/c1-29-21-10-13-9-20(15-6-2-3-7-16(15)23)26(19(13)11-17(21)24)12-14-5-4-8-18(25-14)22(27)28/h2-11H,12H2,1H3,(H,27,28)
Affinity DataIC50: 28nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair