BDBM122423 US8729078, I-33

SMILES Cc1ccc(Nc2nn(cc2C(N)=O)-c2cccc(c2CO)-n2ncc3cc(cc(F)c3c2=O)C(C)(C)C)nc1

InChI Key InChIKey=SHABIGCGANPNDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 122423   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM122423(US8729078, I-33)
Affinity DataIC50:  0.240nMpH: 7.2Assay Description:Plates assayed are 96-well polypropylene (Greiner) and 96-well 1.2 μm hydrophilic PVDF filter plates (Millipore). Concentrations reported here a...More data for this Ligand-Target Pair
In DepthDetails US Patent