BDBM1229 (Hydroxyethyl)amidosuccinoyl deriv. 1::benzyl N-[(1S)-1-{[(2S,3R)-4-[(2S)-2-(tert-butylcarbamoyl)piperidin-1-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamoyl}-2-methylpropyl]carbamate

SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN1CCCC[C@H]1C(=O)NC(C)(C)C

InChI Key InChIKey=DHGYJQQCTRWFTI-FKWFRFQNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1229   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM1229((Hydroxyethyl)amidosuccinoyl deriv. 1 | benzyl N-[...)
Affinity DataIC50:  62nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Cleavage products and substrate w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed