BDBM123786 AAP1742
SMILES Nc1n[nH]c(N)c1\N=N\c1ccncc1
InChI Key InChIKey=RZLCSJZALMLKCU-OUKQBFOZSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 123786
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Institute Of Experimental Botany Ascr And Palacky University
Institute Of Experimental Botany Ascr And Palacky University
Affinity DataIC50: 1.33E+3nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Institute Of Experimental Botany Ascr And Palacky University
Institute Of Experimental Botany Ascr And Palacky University
Affinity DataIC50: 549nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Institute Of Experimental Botany Ascr And Palacky University
Institute Of Experimental Botany Ascr And Palacky University
Affinity DataIC50: 454nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Institute Of Experimental Botany Ascr And Palacky University
Institute Of Experimental Botany Ascr And Palacky University
Affinity DataIC50: 1.49E+4nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Palack�
Curated by ChEMBL
Palack�
Curated by ChEMBL
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Palack�
Curated by ChEMBL
Palack�
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Palack�
Curated by ChEMBL
Palack�
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Institute Of Experimental Botany Ascr And Palacky University
Institute Of Experimental Botany Ascr And Palacky University
Affinity DataIC50: 280nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair