BDBM1244 (Hydroxyethyl)amidosuccinoyl deriv. 16::benzyl N-[(1S)-1-{[(2S,3R)-4-[(2R)-2-tert-butyl-N-(pentan-3-yl)butanediamido]-3-hydroxy-1-phenylbutan-2-yl]carbamoyl}-2-methylpropyl]carbamate
SMILES CCC(CC)NC(=O)C[C@@H](C(=O)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(C)(C)C
InChI Key InChIKey=COOPLUBZYCIUFU-LLEAZYAYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 1244
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)
Boehringer Ingelheim (Canada)
Affinity DataIC50: 2.90nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Cleavage products and substrate w...More data for this Ligand-Target Pair