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BDBM125192 US8765744, 99

SMILES: C[C@H](N1CC[C@]2(CC[C@H](O)CC2)OC1=O)c1ccccc1

InChI Key: InChIKey=YMIDCXIECWAECW-JLJPHGGASA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125192   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (Human))
BDBM125192
PNG
(US8765744, 99)
Show SMILES C[C@H](N1CC[C@]2(CC[C@H](O)CC2)OC1=O)c1ccccc1
Show InChI InChI=1S/C17H23NO3/c1-13(14-5-3-2-4-6-14)18-12-11-17(21-16(18)20)9-7-15(19)8-10-17/h2-6,13,15,19H,7-12H2,1H3/t13-,15-,17+/m0/s1
PDB
MMDB

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Similars

US Patent
n/an/a 1.37E+3n/an/an/an/a6.0n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
In vitro inhibition of 11beta -HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internation...


US Patent US8765744 (2014)


BindingDB Entry DOI: 10.7270/Q2765D0Q
More data for this
Ligand-Target Pair