BDBM12567 2-[(6-chloronaphthalene-2-)[(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl]sulfonamido]acetic acid::GTC000002A::pyrrolidin-2-one-based inhibitor 26

SMILES C[C@H](N1CC[C@H](N(CC(O)=O)S(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)C(=O)N1CCOCC1

InChI Key InChIKey=UAYCGHBBLVJXTC-YWZLYKJASA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12567   

TargetCoagulation factor X(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM12567(2-[(6-chloronaphthalene-2-)[(3S)-1-[(2S)-1-(morpho...)
Affinity DataKi:  2nM ΔG°:  -11.9kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM12567(2-[(6-chloronaphthalene-2-)[(3S)-1-[(2S)-1-(morpho...)
Affinity DataIC50:  4.36nMAssay Description:D3R246More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM12567(2-[(6-chloronaphthalene-2-)[(3S)-1-[(2S)-1-(morpho...)
Affinity DataIC50:  14.3nMAssay Description:D3R245More data for this Ligand-Target Pair
In DepthDetails PubMed