BDBM126612 US8772283, 56

SMILES CNC(=O)c1ccc2-c3nc(c(-c4ccccc4)n3COc2c1)-c1ccc(cc1)C1(N)CC(C)(O)C1

InChI Key InChIKey=CRSVALMQETXTPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126612   

TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM126612(US8772283, 56)
Affinity DataIC50:  0.490nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM126612(US8772283, 56)
Affinity DataIC50:  1.80nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent