BDBM12688 1-(3-amino-1,2-benzoxazol-5-yl)-N-(4-{2-[(dimethylamino)methyl]phenyl}-2-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::Aminobenzisoxazole 2g::BMS-740808 Analogue 15
SMILES CN(C)Cc1ccccc1-c1ccc(NC(=O)c2cc(nn2-c2ccc3onc(N)c3c2)C(F)(F)F)c(F)c1
InChI Key InChIKey=LDUWBIVGHVTDNA-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 12688
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Bristol-Myers Squibb Pharmaceutical Research Institute
Affinity DataKi: 0.210nM ΔG°: -13.1kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Bristol-Myers Squibb Pharmaceutical Research Institute
Affinity DataKi: 0.260nM ΔG°: -12.9kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair