BDBM12754 1-(3-carbamimidoylphenyl)-N-(2-fluoro-4-{1H-imidazo[4,5-b]pyridin-1-yl}phenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::pyrazole analog 3c

SMILES NC(=N)c1cccc(c1)-n1nc(cc1C(=O)Nc1ccc(cc1F)-n1cnc2ncccc12)C(F)(F)F

InChI Key InChIKey=GJMQGXYHAINXFV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12754   

TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM12754(1-(3-carbamimidoylphenyl)-N-(2-fluoro-4-{1H-imidaz...)
Affinity DataKi:  0.0240nM ΔG°:  -14.3kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM12754(1-(3-carbamimidoylphenyl)-N-(2-fluoro-4-{1H-imidaz...)
Affinity DataKi:  7.90nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed