BDBM127943 US8796310, 1F

SMILES Cc1cc(Nc2cc(ccn2)-n2cccn2)nc(c1)-c1cnc(s1)C1(O)CCCc2cc(ccc12)C(O)=O

InChI Key InChIKey=LXIZGPMVTRFUJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127943   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM127943(US8796310, 1F)
Affinity DataIC50: <0.5nMpH: 7.5Assay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Cama Bio...More data for this Ligand-Target Pair
In DepthDetails US Patent