BDBM1283 3-[(1,3-benzoxazol-2-ylmethyl)amino]-5-ethyl-6-methyl-1,2-dihydropyridin-2-one::3-{[1,3-benzoxazol-2-yl)-methyl]amino}-5-ethyl-6-methylpyridin-2(1H)-one::CHEMBL415320::L-696,040::Pyridinone deriv.
SMILES CCc1cc(NCc2nc3ccccc3o2)c(=O)[nH]c1C
InChI Key InChIKey=HXVYWXSMFWAGFQ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 1283
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 210nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 210nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Merck Reserch Laboratories
Curated by ChEMBL
Merck Reserch Laboratories
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Merck Reserch Laboratories
Curated by ChEMBL
Merck Reserch Laboratories
Curated by ChEMBL
Affinity DataIC50: 209nMAssay Description:Inhibition of HIV-1 reverse transcriptase (HIV-1 RT)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 210nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair