BDBM1284 3-Aminopyridin-2(1H)-one analogue 4::3-[(1-benzofuran-2-ylmethyl)amino]-5-ethyl-6-methyl-1,2-dihydropyridin-2-one::CHEMBL316785::Pyridinone deriv. 8

SMILES CCc1cc(NCc2cc3ccccc3o2)c(=O)[nH]c1C

InChI Key InChIKey=QTDHSVQLRCNIKE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 1284   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1284(3-Aminopyridin-2(1H)-one analogue 4 | 3-[(1-benzof...)
Affinity DataIC50:  330nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Organon Research And Development Group

Curated by ChEMBL
LigandPNGBDBM1284(3-Aminopyridin-2(1H)-one analogue 4 | 3-[(1-benzof...)
Affinity DataIC50:  331nMAssay Description:Inhibition of HIV-1 reverse transcriptase (HIV-1 RT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1284(3-Aminopyridin-2(1H)-one analogue 4 | 3-[(1-benzof...)
Affinity DataIC50:  235nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed