BDBM12893 (5S)-N-[(1S,2R)-3-[[(Benzo[1,3]dioxole-5-sulfonyl)](isobutyl)-amino]-1-benzyl-2-hydroxypropyl]-2-oxo-3-[(3-trifluoromethyl)-phenyl]oxazolidine-5-carboxamide::(5S)-N-[(2S,3R)-4-[2H-1,3-benzodioxole-5-(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]-2-oxo-3-[3-(trifluoromethyl)phenyl]-1,3-oxazolidine-5-carboxamide::N-Aryl-oxazolidinone-5-carboxamide Analogue 26d

SMILES CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(C(=O)O1)c1cccc(c1)C(F)(F)F)S(=O)(=O)c1ccc2OCOc2c1

InChI Key InChIKey=IAINWMUGEQGIGE-HFASVGIHSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12893   

TargetHIV-1 protease(Human immunodeficiency virus)
Umbi

Curated by ChEMBL
LigandPNGBDBM12893((5S)-N-[(1S,2R)-3-[[(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  0.0158nMAssay Description:Inhibition of HIV1 protease Q7K mutant by FRET methodMore data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
Umbi

Curated by ChEMBL
LigandPNGBDBM12893((5S)-N-[(1S,2R)-3-[[(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  0.0160nMAssay Description:Inhibition of HIV1 protease Q7K mutant by FRET methodMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [491-589,Q496K](Human immunodeficiency virus type 1)
University Of Massachusetts Medical School

LigandPNGBDBM12893((5S)-N-[(1S,2R)-3-[[(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  0.0160nMAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair