BDBM1291 3-Aminopyridin-2(1H)-one analogue 11::5-ethyl-6-methyl-3-{[(4-oxo-4H-chromen-3-yl)methyl]amino}-1,2-dihydropyridin-2-one

SMILES CCc1cc(NCc2coc3ccccc3c2=O)c(=O)[nH]c1C

InChI Key InChIKey=GPOGYELAMQPQPR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1291   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1291(3-Aminopyridin-2(1H)-one analogue 11 | 5-ethyl-6-m...)
Affinity DataIC50:  1.10E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed