BDBM130377 N-[2-Benzyl-4-(methylsulfonylcarbamoyl)phenyl]-6-(cyclohexylmethyl)pyridine-2- carboxamide (3)

SMILES CS(=O)(=O)NC(=O)c1ccc(NC(=O)c2cccc(CC3CCCCC3)n2)c(Cc2ccccc2)c1

InChI Key InChIKey=ZNGZJFRXFZQBMG-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 130377   

TargetProtein UL24 homolog(Human herpesvirus 8)
University Of California San Francisco

LigandPNGBDBM130377(N-[2-Benzyl-4-(methylsulfonylcarbamoyl)phenyl]-6-(...)
Affinity DataIC50:  3.70E+3nMpH: 8.0Assay Description:Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEpstein-Barr nuclear antigen 1(Human herpesvirus 4)
University Of California San Francisco

LigandPNGBDBM130377(N-[2-Benzyl-4-(methylsulfonylcarbamoyl)phenyl]-6-(...)
Affinity DataIC50:  1.90E+4nMpH: 8.0Assay Description:Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
University Of California San Francisco

LigandPNGBDBM130377(N-[2-Benzyl-4-(methylsulfonylcarbamoyl)phenyl]-6-(...)
Affinity DataIC50:  3.90E+4nMpH: 8.0Assay Description:Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed