BDBM130383 4methyl6{[(3R,4R)4{[5(4methylpyridin2 yl)pentyl]oxy}pyrrolidin3yl]methyl}pyridin2amine ((3R,4R)-3)
SMILES Cc1ccnc(CCCCCO[C@H]2CNC[C@H]2Cc2cc(C)cc(N)n2)c1
InChI Key InChIKey=ZWYPXJQSZOXLSP-NQIIRXRSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 130383
Affinity DataKd: 198nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
3D Structure (crystal)TargetNitric oxide synthase, endothelial [1-973,L111A](Bos taurus (bovine))
University Of California Irvine
University Of California Irvine
Affinity DataKd: 7.27E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
Affinity DataKd: 5.58E+4nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
TargetIsoform PNNOS of Nitric oxide synthase, brain (PNNOS) -973,I269V,M336V,D597N](Rattus norvegicus (rats))
University Of California Irvine
University Of California Irvine
Affinity DataKd: 393nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair