BDBM130911 US8822500, [2]

SMILES C[C@@H](Cc1c(F)c(F)cc(F)c1F)Nc1cc[nH]c(=O)c1-c1nc2cc3C(=O)N(CCN(C)C)C(=O)c3cc2[nH]1

InChI Key InChIKey=VPSBGHLBHGDFAF-LBPRGKRZSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 130911   

TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Chembridge

US Patent
LigandPNGBDBM130911(US8822500, [2])
Affinity DataIC50:  14.0nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chembridge

US Patent
LigandPNGBDBM130911(US8822500, [2])
Affinity DataIC50:  12.2nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chembridge

US Patent
LigandPNGBDBM130911(US8822500, [2])
Affinity DataIC50:  14.0nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Chembridge

US Patent
LigandPNGBDBM130911(US8822500, [2])
Affinity DataIC50:  25.8nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Chembridge

US Patent
LigandPNGBDBM130911(US8822500, [2])
Affinity DataIC50:  0.436nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent