BDBM1314 3-[[(4,7-Dimethylbenzoxazol-2-yl)-methyl]amino]-5-ethyl-6-methylpyridin-2(1H)-one::3-{[(4,7-dimethyl-1,3-benzoxazol-2-yl)methyl]amino}-5-ethyl-6-methyl-1,2-dihydropyridin-2-one::3benzoxazolMeNH deriv.::L-697,639::Pyridinone deriv.

SMILES CCc1cc(NCc2nc3c(C)ccc(C)c3o2)c(=O)[nH]c1C

InChI Key InChIKey=VDZJXIOFISBBLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1314   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Sharp And Dohme Research Laboratories

LigandPNGBDBM1314(3-[[(4,7-Dimethylbenzoxazol-2-yl)-methyl]amino]-5-...)
Affinity DataIC50:  20nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Sharp And Dohme Research Laboratories

LigandPNGBDBM1314(3-[[(4,7-Dimethylbenzoxazol-2-yl)-methyl]amino]-5-...)
Affinity DataIC50:  20nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed