BDBM132304 US8841312, 47

SMILES C1CCC(C1)n1c2ccccc2c2cnc(Nc3ccc(cc3)N3CCNCC3)nc12

InChI Key InChIKey=XEJXFSVXCFISJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 132304   

TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM132304(US8841312, 47)
Affinity DataIC50:  3.70nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM132304(US8841312, 47)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent