BDBM13276 BMS-354825 2-Heteroarylamino-thiazole Analog 12u::N-(2-Chloro-6-methylphenyl)-2-(2-methyl-6-(3-morpholinopropyl)-pyrimidin-4-ylamino)-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-[(2-methyl-6-{[3-(morpholin-4-yl)propyl]amino}pyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide

SMILES Cc1nc(NCCCN2CCOCC2)cc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)n1

InChI Key InChIKey=CRHCQKSSAJEGRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13276   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM13276(BMS-354825 2-Heteroarylamino-thiazole Analog 12u |...)
Affinity DataIC50:  0.700nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed