BDBM13337 3-(benzyloxy)pyridin-2-amine::EN300-247019::Pyridine derived fragment based inhibitor 1
SMILES Nc1ncccc1OCc1ccccc1
InChI Key InChIKey=NMCBWICNRJLKKM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 13337
Affinity DataIC50: 1.30E+6nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
Affinity DataIC50: 6.19E+5nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
Affinity DataIC50: 3.08E+5nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MAPK p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+6nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataKd: 6.92E+5nMAssay Description:Binding affinity to Bcl-xL by 2D- NOESY analysisMore data for this Ligand-Target Pair