BDBM1352 3-Aminopyridin-2(1H)-one analogue 72::3-[(2-Naphthylmethyl)amino]-1,6-dimethyl-5-ethylpyridin-2(1H)-one::5-ethyl-1,6-dimethyl-3-[(naphthalen-2-ylmethyl)amino]-1,2-dihydropyridin-2-one

SMILES CCc1cc(NCc2ccc3ccccc3c2)c(=O)n(C)c1C

InChI Key InChIKey=NNQNCAAPOLAXLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1352   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1352(3-Aminopyridin-2(1H)-one analogue 72 | 3-[(2-Napht...)
Affinity DataIC50:  1.10E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed