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BDBM135571 US8853258, 224

SMILES: CC(CCc1ccc(cc1)C1=CCCCC1)(C(=O)NO)S(C)(=O)=O

InChI Key: InChIKey=ZTMQOZNKZMKWHO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 135571   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM135571
PNG
(US8853258, 224)
Show SMILES CC(CCc1ccc(cc1)C1=CCCCC1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C18H25NO4S/c1-18(17(20)19-21,24(2,22)23)13-12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h6,8-11,21H,3-5,7,12-13H2,1-2H3,(H,19,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.441n/an/an/an/a8.0n/a



Pfizer Inc

US Patent


Assay Description
IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...


US Patent US8853258 (2014)


BindingDB Entry DOI: 10.7270/Q25M64DP
More data for this
Ligand-Target Pair