BDBM13581 4-({[4-(benzyloxy)-2-methanesulfonamido-5-methoxyphenyl]methyl}amino)benzene-1-carboximidamide::benzylamine 7

SMILES COc1cc(CNc2ccc(cc2)C(N)=N)c(NS(C)(=O)=O)cc1OCc1ccccc1

InChI Key InChIKey=CRFICMUDNBIMKL-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13581   

TargetCoagulation factor VII(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13581(4-({[4-(benzyloxy)-2-methanesulfonamido-5-methoxyp...)
Affinity DataKi:  380nM ΔG°:  -8.66kcal/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

LigandPNGBDBM13581(4-({[4-(benzyloxy)-2-methanesulfonamido-5-methoxyp...)
Affinity DataKi:  400nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13581(4-({[4-(benzyloxy)-2-methanesulfonamido-5-methoxyp...)
Affinity DataKi:  1.40E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13581(4-({[4-(benzyloxy)-2-methanesulfonamido-5-methoxyp...)
Affinity DataKi:  2.60E+4nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed