BDBM13814 ({4-[(4E)-2-(1H-1,2,3-benzotriazol-1-yl)-2-[4-(methoxycarbonyl)phenyl]-5-phenylpent-4-en-1-yl]phenyl}difluoromethyl)phosphonic acid::benzotriazole phenyldifluoromethylphosphonic acid compound 1
SMILES COC(=O)c1ccc(cc1)C(C\C=C\c1ccccc1)(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)n1nnc2ccccc12
InChI Key InChIKey=GWWTUJWRRCTCSI-JXMROGBWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 13814
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 39nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 87nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [L119V](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 142nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2 [V121L](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 24nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 87nMAssay Description:Inhibition of human TCPTP (1 to 296 residues) catalytic domain expressed in Escherichia coli BL21 cells using fluorescein diphosphate as substrate by...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [M114V](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 45nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [V113L,M114V](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 29nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [G117E](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 32nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of flag-tagged human PTP1B (1 to 298 residues) catalytic domain expressed in Escherichia coli BL21 cells using fluorescein diphosphate as ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [V113I](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 39nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair