BDBM13941 APC-8249::{amino[2-(2-hydroxy-5-nitrophenyl)-1H-1,3-benzodiazol-5-yl]methylidene}azanium

SMILES NC(=[NH2+])c1ccc2nc([nH]c2c1)-c1cc(ccc1O)[N+]([O-])=O

InChI Key InChIKey=XDLJIVLILSOHRM-UHFFFAOYSA-O

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13941   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13941(APC-8249 | {amino[2-(2-hydroxy-5-nitrophenyl)-1H-1...)
Affinity DataKi:  340nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13941(APC-8249 | {amino[2-(2-hydroxy-5-nitrophenyl)-1H-1...)
Affinity DataKi:  940nM ΔG°:  -8.13kcal/molepH: 6.1 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13941(APC-8249 | {amino[2-(2-hydroxy-5-nitrophenyl)-1H-1...)
Affinity DataKi:  2.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13941(APC-8249 | {amino[2-(2-hydroxy-5-nitrophenyl)-1H-1...)
Affinity DataKi:  2.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed