BDBM139601 US8889870, 147::US9820989, 147

SMILES Cc1ccc(cc1N1CCc2nc(N)ncc2C1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=TVTINSXYADVJDH-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 139601   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM139601(US8889870, 147 | US9820989, 147)
Affinity DataKi:  8nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM139601(US8889870, 147 | US9820989, 147)
Affinity DataKi:  20nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM139601(US8889870, 147 | US9820989, 147)
Affinity DataIC50:  8nMpH: 7.4Assay Description:Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 .mu.g/well of poly-Glu-Tyr (4:1) in 10 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM139601(US8889870, 147 | US9820989, 147)
Affinity DataIC50:  20nMpH: 7.4Assay Description:Biochemical PDGFR.beta. kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 .mu.g of poly-Glu-Tyr (4:1) in 1...More data for this Ligand-Target Pair
In DepthDetails US Patent