BDBM140217 US8906911, 26

SMILES CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1ccnc(c1)C(F)(F)F

InChI Key InChIKey=DTQIINKFPZNNKS-WSMPKYOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140217   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140217(US8906911, 26)
Affinity DataKi:  792nM ΔG°:  -7.73kcal/mole IC50:  598nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent