BDBM14191 N-{7-cyclohexyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}-4-(2-methoxyethyl)piperazin-1-amine::pyrrolopyrimidine 14
SMILES COCCN1CCN(CC1)Nc1ncc2ccn(C3CCCCC3)c2n1
InChI Key InChIKey=VDNDJYFLOAXKKR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 14191
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Johnson & Johnson Pharmaceutical
Affinity DataIC50: 110nMAssay Description:The compounds were tested for their ability to inhibit the phosphorylation of serine 795 of Rb by purified recombinant CDK4. The phosphorylation of s...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the phosphorylation of serine 10 of histone-H3 by purified recombinant murine Aurora-A enzyme....More data for this Ligand-Target Pair