BDBM14315 CRA26::methyl N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-ylcarbamoyl)phenyl]methyl}-1,2,4-oxadiazol-3-yl)-1-oxo-4-(pyrrolidin-3-yl)butan-2-yl]carbamate

SMILES COC(=O)N[C@@H](CCC1CCNC1)C(=O)c1noc(Cc2ccc(cc2)C(=O)NC2Cc3ccccc3C2)n1

InChI Key InChIKey=FMOHDCRLFIUBOX-WIIYFNMSSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14315   

TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14315(CRA26 | methyl N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-in...)
Affinity DataKi:  130nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14315(CRA26 | methyl N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-in...)
Affinity DataKi:  5.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed