BDBM14318 CRA29::N-[(2S)-4-(azetidin-3-yl)-1-(5-{[4-(2,3-dihydro-1H-inden-2-ylcarbamoyl)phenyl]methyl}-1,2,4-oxadiazol-3-yl)-1-oxobutan-2-yl]-3,4-difluorobenzamide

SMILES Fc1ccc(cc1F)C(=O)N[C@@H](CCC1CNC1)C(=O)c1noc(Cc2ccc(cc2)C(=O)NC2Cc3ccccc3C2)n1

InChI Key InChIKey=PAARNHKSQBTMJE-NDEPHWFRSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14318   

TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14318(CRA29 | N-[(2S)-4-(azetidin-3-yl)-1-(5-{[4-(2,3-di...)
Affinity DataKi:  590nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14318(CRA29 | N-[(2S)-4-(azetidin-3-yl)-1-(5-{[4-(2,3-di...)
Affinity DataKi:  1.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed