BDBM14325 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}-6-phenylbenzen-1-olate::CRA-7806

SMILES NC(=[NH2+])c1ccc2nc([nH]c2c1)-c1cccc(-c2ccccc2)c1[O-]

InChI Key InChIKey=LMGQGPVCSYOMNS-UHFFFAOYSA-N

Data  5 KI

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14325   

TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14325(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  74nM ΔG°:  -9.62kcal/molepH: 7.5 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14325(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  450nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14325(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  1.60E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14325(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  5.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14325(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  1.10E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed