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BDBM143265 US9682953, 2.B-13

SMILES: FC(F)(F)c1ccc(Oc2cccc(C=C3CCC(CC3)NC(=O)c3ccc(nc3)-n3cnnc3)c2)nc1

InChI Key: InChIKey=BOCWHKDIBVAVFW-PDGQHHTCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 143265   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Rattus norvegicus (rat))
BDBM143265
PNG
(US9682953, 2.B-13)
Show SMILES FC(F)(F)c1ccc(Oc2cccc(C=C3CCC(CC3)NC(=O)c3ccc(nc3)-n3cnnc3)c2)nc1
Show InChI InChI=1S/C27H23F3N6O2/c28-27(29,30)21-7-11-25(32-15-21)38-23-3-1-2-19(13-23)12-18-4-8-22(9-5-18)35-26(37)20-6-10-24(31-14-20)36-16-33-34-17-36/h1-3,6-7,10-17,22H,4-5,8-9H2,(H,35,37)/b18-12-
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 14n/an/an/an/a7.425



Advinus Therapeutics Ltd

US Patent


Assay Description
All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...


US Patent US9682953 (2017)


BindingDB Entry DOI: 10.7270/Q2BR8QBH
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM143265
PNG
(US9682953, 2.B-13)
Show SMILES FC(F)(F)c1ccc(Oc2cccc(C=C3CCC(CC3)NC(=O)c3ccc(nc3)-n3cnnc3)c2)nc1
Show InChI InChI=1S/C27H23F3N6O2/c28-27(29,30)21-7-11-25(32-15-21)38-23-3-1-2-19(13-23)12-18-4-8-22(9-5-18)35-26(37)20-6-10-24(31-14-20)36-16-33-34-17-36/h1-3,6-7,10-17,22H,4-5,8-9H2,(H,35,37)/b18-12-
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/a7.425



Advinus Therapeutics Ltd

US Patent


Assay Description
All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...


US Patent US9682953 (2017)


BindingDB Entry DOI: 10.7270/Q2BR8QBH
More data for this
Ligand-Target Pair