BDBM14334 2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-indol-2-yl}-6-(cyclopentyloxy)benzen-1-olate::CRA-10991

SMILES NC(=[NH2+])c1cc2cc([nH]c2cc1Cl)-c1cccc(OC2CCCC2)c1[O-]

InChI Key InChIKey=QXAURVOBXQBPAP-UHFFFAOYSA-N

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14334   

TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14334(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-indol-2-...)
Affinity DataKi:  21nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14334(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-indol-2-...)
Affinity DataKi:  160nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14334(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-indol-2-...)
Affinity DataKi:  2.30E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14334(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-indol-2-...)
Affinity DataKi:  6.00E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14334(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-indol-2-...)
Affinity DataKi:  2.40E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed