BDBM14341 (2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}-5-(2-methoxyphenyl)-4-oxidophenyl)butanedioate::CRA-17312

SMILES COc1ccccc1-c1cc(cc(-c2nc3ccc(cc3[nH]2)C(N)=[NH2+])c1[O-])[C@@H](CC([O-])=O)C([O-])=O

InChI Key InChIKey=HVNXYZZCSQONQC-OAHLLOKOSA-L

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14341   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14341((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  750nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14341((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  780nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14341((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  3.50E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14341((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  8.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14341((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi: >7.50E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed