BDBM14346 (2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-5-bromo-4-oxidophenyl)butanedioate::CRA-19858

SMILES NC(=[NH2+])c1ccc2[nH]c(cc2c1)-c1cc(cc(Br)c1[O-])[C@@H](CC([O-])=O)C([O-])=O

InChI Key InChIKey=OQKMBFOTVQYDAF-LLVKDONJSA-L

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 14346   

TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14346((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-indol-2-y...)
Affinity DataKi:  48nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14346((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-indol-2-y...)
Affinity DataKi:  240nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14346((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-indol-2-y...)
Affinity DataKi:  1.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14346((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-indol-2-y...)
Affinity DataKi:  1.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed